Prenatal Intervention for Lower Urinary Tract Obstruction
نویسندگان
چکیده
Hydronephrosis is one of the most common abnormalities detected on routine prenatal ultrasounds, being noted in up to 1% of fetuses. Rarely, severe hydronephrosis coexists with oligohydramnios, which portends a poor prognosis. We review the most recent literature on the results of prenatal intervention in this setting. Presently, the first randomized controlled trial to address whether prenatal vesicoamniotic shunting improves survival and renal function is underway, and should address the value of prenatal intervention.
منابع مشابه
Lower urinary tract obstruction (LUTO) – prenatal intervention and long term outcome
Lower urinary tract obstruction in foetuses carries an untreated high rate of mortality. Ultrasound antenatal examination allows to introduce treatment in utero. Authors describe different therapeutics options and emphasize necessity of proper qualification to prenatal procedures. The role of antenatal therapy in LUTO was evaluated.
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Lower urinary tract obstruction is defined as partial or complete obstruction of the urinary tract at the level of the urethra and the bladder. The posterior urethral valves are the most common cause, 9 percent of the fetal uropathies. The incidence range is wide, because of different databases show different populations. The most severe obstructive uropathy is in patients with kidney damage, o...
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OBJECTIVE To estimate the effect of prenatal bladder drainage on perinatal survival in fetuses with lower urinary tract obstruction. DATA SOURCES Relevant articles were identified by searching the databases MEDLINE (1966-2002), EMBASE (1988-2002), and the Cochrane library (2000;4). METHODS OF STUDY SELECTION Studies were selected if the effect of prenatal bladder drainage (vesicocentesis, v...
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BACKGROUND Congenital lower urinary tract obstruction is associated with high mortality and morbidity. Antenatal detection has improved with advances in ultrasound technology, and has allowed the option of antenatal intervention. OBJECTIVES To systematically review the literature to evaluate the effectiveness of antenatal interventions to improve perinatal survival and postnatal renal functio...
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Fetal lower urinary tract obstruction (LUTO) is a serious condition, which commonly results in marked perinatal morbidity and mortality. The characteristic prenatal presentation of LUTO includes an enlarged bladder with bilateral obstructive uropathy. While mild forms of the disease result in minimal clinical sequelae, the more severe forms commonly lead to oligohydramnios, dysplastic changes i...
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